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Constructing and Validating a Prediction Model for Acute Heart Failure in Patients with Hypertrophic Cardiomyopathy: Propensity Score Matching, Internal Validation, and Case-Control Study

Constructing and Validating a Prediction Model for Acute Heart Failure in Patients with Hypertrophic Cardiomyopathy: Propensity Score Matching, Internal Validation, and Case-Control Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106648
Enrollment
Unknown
Registered
2025-07-28
Start date
2025-01-26
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Heart Failure in Patients with Hypertrophic Cardiomyopathy

Interventions

Heart failure group and non heart failure group:No

Sponsors

Wuhan Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. A left ventricular wall thickness of >=15 mm at any site during diastole as shown by echocardiography or magnetic resonance imaging can confirm the diagnosis. 2. A positive genetic test for a pathogenic variant or a left ventricular wall thickness of >=13 mm found in a family member with genetic involvement can also confirm the diagnosis (referring to the diagnostic criteria in the 2023 ESC Guidelines for the Management of Cardiomyopathies); 3. age >18 years.

Exclusion criteria

Exclusion criteria: 1. Incomplete medical records; 2. Presence of active malignancy and severe hepatic or renal insufficiency, or infection; 3. Impaired consciousness or inability to communicate; 4. Acute heart failure caused by other diseases such as myocardial infarction, pericarditis, myocarditis, or stage 5 renal failure.

Design outcomes

Primary

MeasureTime frame
BNP;Troponin I;age;history of tobacco use;use of diuretics;LVEF;LVOTO;IVS thickness;coexisting coronary myocardial bridge;history of syncope;myocardial ischemia;

Countries

China

Contacts

Public ContactChen Zhen

Wuhan Central Hospital, Hubei Province

2716201445@qq.com+86 152 7350 8661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 14, 2026