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Effect of hydromorphone combined with Ropivacaine block on postoperative analgesia of gynecological malignant tumor

Effect of hydromorphone combined with Ropivacaine block on postoperative analgesia of gynecological malignant tumor

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106641
Enrollment
Unknown
Registered
2025-07-28
Start date
2023-11-07
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic malignant tumor

Interventions

Exposure group (hydromorphone combined with ropivacaine group):None
Non-exposed group (ropivacaine group):None

Sponsors

Yan 'an University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18~65 years old 2.BMI: 18.5~30.0kg/? 3.ASA: Grade I ~ III 4.Patients with gynecological malignant tumor undergoing radical surgery 5.Sign informed consent

Exclusion criteria

Exclusion criteria: 1.There is a history of fine, hemp drug abuse 2.Allergic to amide narcotics and opioid narcotic drugs 3.Coagulation dysfunction 4. Abnormal liver and kidney function 5.Operation site infection 6.Patients with cardiovascular and cerebrovascular diseases 7.Refuse to participate in this trial

Design outcomes

Primary

MeasureTime frame
The consumption of sufentanil 48 hours after the operation;

Secondary

MeasureTime frame
VAS scores at different time points after surgery ;Time and number of first compressions of the analgesic pump;Intraoperative dosage of remifentanil and propofol;Overall satisfaction scores of patients with analgesia;Time of first eating ;Time of first intake;Time of first anal exhaust;PACU stay time;The first time to get out of bed ;The number of days in hospital;Hematoma;Bleeding;Local anesthetic poisoning;Nausea and vomiting;Skin itch;Lower limb motor block;

Countries

China

Contacts

Public ContactLuo Zhikai/ Gong Dehui

Yan 'an University Affiliated Hospital

lzk2821@126.com+86 138 9117 1821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026