Sarcopenia
Conditions
Interventions
Non-sarcopenia observation group:None
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=60 years old; 2. The patient has the first onset of the disease, meets the diagnostic criteria for stroke in the World Health Organization (WHO) or the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2022 Edition), and is confirmed to be ischemic stroke by head CT or MRI examination; 3. The course of the disease is >=2 weeks, and the condition is stable; 4. The patient has normal cognition, and the Mini-Task Mental State Examination (MMSE) score is >=20 points; 5. Ability to stand up with no or little assistance and cooperate with all examiners.
Exclusion criteria
Exclusion criteria: 1. Severe liver and kidney failure, malignant tumors (advanced), severe infections, and other diseases that may significantly affect muscle metabolism and systemic nutritional status. 2. Previous primary neuromuscular diseases such as congenital myopathy, myasthenia gravis, and polymyositis. 3. Muscle mass assessment cannot be performed due to severe limb deformity, extensive skin damage, burns, etc.; Due to head trauma, skull defects, wearing a pacemaker, etc., it is impossible to complete the cortical oxygen hemoglobin determination of near-infrared brain function imaging. 4. Severe malnutrition (such as serum albumin <25g/L), hyperthyroidism, etc., which may independently affect muscle mass; or uncontrolled complications such as status epilepticus and severe cerebral edema after stroke.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenated hemoglobin concentration;lateralization index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Handgrip strength;Micronutrient Scale score;Appendicular skeletal muscle mass index;Mini-mental state assessment scale score; | — |
Countries
China
Contacts
Public ContactZhang Yunyun
The First People’s Hospital of Lianyungang
Outcome results
None listed