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Predictive effect of quadriceps muscle depth and perioperative EEG characteristics on postoperative delirium in elderly patients: a prospective cohort study

Predictive effect of quadriceps muscle depth and perioperative EEG characteristics on postoperative delirium in elderly patients: a prospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106607
Enrollment
Unknown
Registered
2025-07-28
Start date
2024-12-09
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=65 years old; 2. ASA grade I~IV; 3. Large-scale abdominal, obstetrics and gynecology, vascular, orthopedic and thoracic surgery is planned to be performed in an elective period; 4. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe hepatic insufficiency (Child-Pugh grade C), severe renal insufficiency (requiring dialysis before surgery), and patients with severe heart failure (METS<4); 2. Patients with delirium before surgery (assessed using the 3D-CAM scale); 3. Patients who lack the ability to give informed consent; 4. Patients who cannot cooperate with the completion of the frailty scale assessment before surgery; 5. Patients who cannot undergo EEG monitoring; 6. Patients with previous mental and neurological diseases: such as cognitive dysfunction (assessed using MMSE scale), depression, severe central nervous system depression, Parkinson's disease, basal ganglion disease, schizophrenia, epilepsy, Alzheimer's disease, myasthenia gravis, etc. taking psychotropic drugs; 7. Received general anesthesia within 30 days before surgery; 8. Patients with any limb amputation, paraplegia, or diseases affecting muscles; 9. Has participated in other researchers.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative delirium;

Secondary

MeasureTime frame
Quality of recovery the day after surgery;Number of days of postoperative hospital stay;Postoperative related complications;

Countries

China

Contacts

Public ContactLiu Xuesheng

The First Affiliated Hospital of Anhui Medical University

liuxuesheng@ahmu.edu.cn+86 186 5519 3385

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 15, 2026