Non-autonomous motion artifacts appear in liver Gd-EOB-DTPA-enhanced MRI.
Conditions
Interventions
Experimental group (scopolamine bromide):Intramuscular injection of scopolamine bromide
Control group:Inject an equal volume of physiological saline intramuscularly.
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Given the significant impact of breathing on imaging, all participants completed breathing exercises before the examination to ensure they could hold their breath for more than 26 seconds in a baseline state. 2.Age 18-60, gender unrestricted. 3.Patients who previously exhibited TSM artifacts (in the most recent examination prior to this one) now need to undergo a gadoteric acid-enhanced MRI of the liver for reevaluation. 4.Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those who are allergic to gadoteric acid disodium or scopolamine butylbromide. 2.Glaucoma, pyloric obstruction, and benign prostatic hyperplasia (with abnormal urination), increased intracranial pressure, acute phase of cerebral hemorrhage. 3.Patients with severe heart disease, tachycardia, organic pyloric stenosis, and paralytic ileus. 4.There may be study participants who could experience adverse reactions from combined medication use, such as those taking antiarrhythmic drugs or tricyclic antidepressants. 5.Individuals with a history of mental illness or those who are unable to cooperate with examinations. 6.Pregnant or breastfeeding women. 7.Liver function Child C grade or bilirubin > 3 mg/dL; patients with impaired renal function (glomerular filtration rate < 30 ml/min/1.73 m^2).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of TSM; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactChen Liu
The First Affiliated Hospital of Army Medical University
Outcome results
None listed