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Construction and Clinical Validation of a Multimodal Imaging AI Diagnostic System for Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Based on Radiomics

Construction and Clinical Validation of a Multimodal Imaging AI Diagnostic System for Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Based on Radiomics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106576
Enrollment
Unknown
Registered
2025-07-25
Start date
2025-07-31
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Anomalies of the Kidney and Urinary tract

Interventions

Observation group (congenital kidney and urinary tract malformations group):None
Control group (non-congenital kidney or urinary tract malformation group):None

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Observation group (1) 0 years old< = age<=90 years old, gender is not limited; (2) Imaging diagnosis of congenital kidney and urinary tract malformations (abnormal kidney development: kidney underdevelopment, hypoplasia, dysplasia and ectopic kidney, etc.; Urinary tract obstructive lesions: renal pelvisureteral junction obstruction (UPJO), vesicoureteral reflux (VUR), posterior urethral valve (PUV), etc.; Abnormal collection system: duplicate renal pelvis ureter, giant ureter, ureteral cyst, etc.); (3) Patients or their legal guardians sign written informed consent and agree to provide clinical data and imaging data for this study; (4) Be able to provide complete clinical data and imaging data. 2. Control group (1) 0 years old< = age<=90 years old, gender is not limited; (2) Patients with non-congenital kidney and urinary tract malformations or patients with acquired factors leading to kidney and urinary tract malformations; (3) Patients or their legal guardians sign written informed consent and agree to provide clinical data and imaging data for this study; (4) Be able to provide complete clinical data and imaging data.

Exclusion criteria

Exclusion criteria: 1. Observation group (1) Non-congenital malformations: acquired kidney or urinary tract diseases (such as stones, tumors, post-traumatic malformations) or urinary tract abnormalities secondary to infection, drugs, or metabolic diseases; (2) Lack of necessary imaging data; (3) The image quality is poor and cannot be annotated. (4) Unable to cooperate with follow-up or refuse to provide necessary clinical information 2. Control group (1) Unable to cooperate with follow-up or refuse to provide necessary clinical information; (2) Lack of necessary imaging data; (3) The image quality is poor and cannot be annotated.

Design outcomes

Primary

MeasureTime frame
Radiological parameters;Subtype classification;

Secondary

MeasureTime frame
Renal function;

Countries

China

Contacts

Public ContactXuesong Li

Peking University First Hospital

pineneedle@sina.com+86 183 5652 9939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026