Coronary heart disease
Conditions
Interventions
Research group B:Ultrasound-guided unilateral thoracic paravertebral block
Research group A:Ultrasound-guided bilateral thoracic paravertebral block
Blank group:No paravertebral nerve block maneuver is performed
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=45 years old; 2. ASA grade: II.I-II; 3. Meet the criteria for the diagnosis of coronary heart disease before surgery; 4. No contraindications to surgery; 5. Bilateral parathoracic block under ultrasound guidance before surgery and the block is effective; 6. Good cooperation with this experiment; 7. No preoperative TnT elevation due to non-ischemic causes (sepsis, electrical cardioversion, pulmonary embolism)
Exclusion criteria
Exclusion criteria: 1. Combined with other malignant tumors and organ dysfunction; 2. Infection at the puncture site; 3. History of thoracolumbar spine surgery; 4. Combined with severe mental illness and poor compliance; 5. Abnormal coagulation function; 6. Long-term use of immunosuppressive drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High-sensitivity cardiac troponin T;High-sensitivity cardiac troponin I; | — |
Secondary
| Measure | Time frame |
|---|---|
| Human high mobility group box 1 protein;Heart-type fatty acid binding protein;N-terminal pro-brain natriuretic peptide; | — |
Countries
China
Contacts
Public ContactWang Qi
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed