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Development of a Multifactorial Predictive Model for Vital Pulpotomy Outcomes in Chronic Pulpitis Cases

Development of a Multifactorial Predictive Model for Vital Pulpotomy Outcomes in Chronic Pulpitis Cases

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106550
Enrollment
Unknown
Registered
2025-07-25
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpal and periapical diseases

Interventions

Intervention group :Pulpotomy

Sponsors

School and Hospital of Stomatology, Fujian Medical University, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Permanent teeth with pulp exposure caused by caries or trauma; 2. Teeth with history of spontaneous or nocturnal pain; 3. Teeth with restorable value; 4. Positive response to electric pulp test, lingering cold-induced pain (lasting seconds); 5. Normal periradicular tissue without significant swelling, sinus tract, or moderate/severe percussion pain; 6. Hemostasis achieved within 5-10 minutes after pulpotomy; 7. Periapical index (PAI) score <=2; 8. No systemic diseases contraindicating dental treatment.

Exclusion criteria

Exclusion criteria: 1. Cases not meeting the above inclusion criteria; 2. Teeth with severe periodontitis, pronounced wedge-shaped defects, excessive attrition, or cracked tooth syndrome; 3. Patients with poor compliance or inability to attend follow-up visits.

Design outcomes

Primary

MeasureTime frame
Biological markers in dental pulp blood(MMP-9,IL-1ß,TNF-a,IL-8);

Secondary

MeasureTime frame
Pain Intensity Score;Pulp sensibility testing ;Periapical index;Root morphology;Hemostasis time;

Countries

China

Contacts

Public ContactLv Hongbing

School and Hospital of Stomatology, Fujian Medical University, China

hongbinglu@126.com+86 136 9686 9093

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026