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Study on the effect of extracorporeal diaphragm pacing therapy on gut microbiota in stroke recovery patients

Study on the effect of extracorporeal diaphragm pacing therapy on gut microbiota in stroke recovery patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106545
Enrollment
Unknown
Registered
2025-07-25
Start date
2024-05-21
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Control Group:Conventional rehabilitation therapy
Intervention group:Conventional rehabilitation therapy and extracorporeal diaphragm pacing

Sponsors

Shanghai Yangzhi Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with stroke by MR/CT, with a duration of 2 weeks = 6 months; 2. Age between 18-80 years old; 3. Experienced invasive mechanical ventilation treatment during the acute phase; 4. Vital signs are relatively stable and expected to be hospitalized for more than 4 weeks; 5. The patient or family member signs and agrees.

Exclusion criteria

Exclusion criteria: 1. The skin at the electrode attachment site is damaged or infected; 2. Previous major thoracic and abdominal surgeries; 3. Patients with severe chronic heart, lung, intestinal diseases or tumors; 4. Moderate or above pleural effusion; 5. Pregnant women or perinatal period; 6. Have suffered from other neurological and muscular diseases; 7. Pacemaker implants; 8. Individuals who have experienced epileptic seizures or are not suitable for electrical stimulation therapy; 9. Recently experienced major gastrointestinal bleeding or angina pectoris; 10. Refusal from patients or family members; 11. The researcher considers it inappropriate to participate in the study.

Design outcomes

Primary

MeasureTime frame
Fecal microbiota;Metabolites;

Secondary

MeasureTime frame
Blood inflammatory indicators;

Countries

China

Contacts

Public ContactFei Chen

Shanghai Yangzhi Rehabilitation Hospital

214975457@qq.com+86 189 1828 9143

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026