Esophageal Cancer
Conditions
Sponsors
Affiliated Cancer Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective radical esophagectomy; 2. Age >= 65 years; 3. BMI 18.5–28 kg/m²; 4. ASA Class II–III.
Exclusion criteria
Exclusion criteria: 1. Pre-existing neuromuscular disorders; 2. Long-term preoperative use of psychotropic drugs, chronic analgesics, or agents affecting neuromuscular transmission; 3. Documented allergy to neuromuscular blocking agents or other anesthetics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The onset time of rocuronium bromide (defined as the time from the injection of rocuronium bromide to when T1% drops to 0).;Average intraoperative dosage of rocuronium bromide (mg/kg/h);Time to 10% recovery (defined as the time from the injection of rocuronium bromide to when T1% recovers to 10%).;Recovery Index (defined as the time from T1% recovering to 25% to T1% recovering to 75%).;Duration of TOF (Train-of-Four) value >= 0.9 (administered sugammadex 2 mg/kg when T2 appears); | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics before and after induction;Intraoperative blood loss;Intraoperative urine output;Hemodynamics before and after induction; | — |
Countries
China
Contacts
Public ContactZhang Minhao
Department of Anesthesiology, Affiliated Cancer Hospital of Nanjing Medical University
Outcome results
None listed