Eye and adnexa
Conditions
Interventions
Intervention Group:Neuropatty soaked with 20mL of TXA 1000mg/10mL preparation applied for 2 minutes
Control Group:Neuropatty soaked with 20ml Normal Saline Solution (NSS) applied for 2 minutes
Sponsors
Department of Ophthalmology and Visual Sciences (DOVS), The Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged = 18 years old, male or female. 2. Patients diagnosed with Primary Acquired Naso Lacrimal Duct Obstruction (NLDO) 3. Patients advised to undergo Endoscopic Endonasal Dacryocystorhinostomy (EEDCR)
Exclusion criteria
Exclusion criteria: 1. Bleeding tendency including hematological disease (thrombocytopenia, hemophilia, clotting disorders) 2. Patients with co-morbidities like uncontrolled hypertension, malignant hyperthermia, acute or chronic renal failure, and familial history of blood dyscrasia. 3. Concomitant sinonasal pathologies requiring additional procedures e.g., septoplasty, turbinoplasty 4. History of previous lacrimal surgery or any endonasal surgeries 5. Secondary causes of nasolacrimal duct obstruction such as previous irradiation, trauma-related bony deformities or laceration to lacrimal passages, systemic chemotherapy, major diseases affective the respective side of nose and orbit 6. Pregnant or breast-feeding patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Blood loss;Intraoperative Blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure, Diastolic Blood Pressure, Systolic Blood Pressure and Heart rate, at 15-minute mark;Recurrence of bleeding after removal nasal packing on post-operative day 1.;1-day post-operative laboratory investigations like bleeding and clotting factors.;Weight of ribbon gauze used for post-operation nasal packing; | — |
Countries
China
Contacts
Public ContactDr CHONG Kam Lung Kelvin
Department of Ophthalmology and Visual Sciences
Outcome results
None listed