Sphincter of Oddi dysfunction
Conditions
Interventions
Control group:Narditest test and Anisodamine
Sphincter of Oddi Dysfunction group:Narditest test and Anisodamine
Sponsors
Southwest Hospital, Army Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Selection criteria for healthy volunteers 1. Age 20-60 years old, regardless of gender 2. Routine examination of liver function, liver enzyme profile and B-ultrasound without abnormal findings. 3. Voluntarily take the test and sign the informed consent form. 4. Fasting and water abstinence for 12 hours before the test. Inclusion criteria for patients with clinically suspected SOD 1. Patients have a history of cholecystectomy and must have episodic epigastric and/or right upper quadrant pain with all of the following: (1) Abdominal pain lasts for at least 30 minutes (2) Symptoms are intermittent and recurrent, with varying intervals (non-daily attacks) (3) Pain worsens to a relatively stable level (4) The pain is moderate or severe, affecting the patient's daily life or causing the patient to seek medical attention in the emergency department (5) Abdominal pain does not relieve after defecation (6) Abdominal pain is not relieved by changes in body position (7) Antacids do not relieve abdominal pain 2. It may be accompanied by transient jaundice and recurrent pancreatitis 3. Exclude organic lesions of the hepatobiliary system 4. Exclude other systemic organic diseases that can cause abdominal pain
Exclusion criteria
Exclusion criteria: 1.Patients with impaired cardiac or pulmonary function who cannot tolerate the procedure. 2.Patients who have taken any antispasmodic medications within 3 days prior to the examination. 3.Patients with poor compliance or inability to complete the required study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oddi sphincter electromyography amplitude;Oddi sphincter electromyographic duration;Oddi sphincter electromyographic frequency;Oddi sphincter basal pressure;Oddi sphincter contraction peak;Oddi sphincter contraction duration; | — |
Countries
China
Contacts
Public ContactChen Fei, Li Hucheng, Dong Jiahong
Southwest Hospital, Third Military Medical University
Outcome results
None listed