Major depression disorder
Conditions
Interventions
active group:Acceleration Treatment Phase: Accelerated treatment for 2 days, with 5 sessions per day, each session consisting of 1800 pulses, for a total of 10 sessions.
Maintenance Treatment Phase: T
sham group:The coil will be rotated 180 degrees and, following the same treatment protocol as the active treatment group, a sham stimulation will be performed continuously for two days. After data col
Sponsors
Tianjin Anding Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Age 12-18 years ; 2. Meet the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnostic criteria for depression and bipolar depression, and the diagnosis is confirmed by the MINI-International Neuropsychiatric Interview (M.I.N.I.-KID); 3. The score of Montgomery-Åsberg Depression Rating Scale should not be less than 22.
Exclusion criteria
Exclusion criteria: 1. Combined with other mental diseases, such as schizophrenia, obsessive-compulsive disorder; 2. Accompanied by serious brain organic diseases, such as epilepsy, stroke, encephalitis, brain trauma, etc., or serious physical diseases such as malignant tumors, acute heart failure, multiple organ failure, etc.; 3. There are contraindications to magnetic resonance scanning such as metal implants and claustrophobia; 4. Those who have received electroconvulsive therapy, transcranial magnetic stimulation or light therapy in the past 6 months; 5. A history of alcohol or drug dependence in the past one year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery-Asberg Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Columbia-Suicide Severity Rating Scale;Patient Health Questionnaire-9;Generalized Anxiety Disorder-7;Beck Scale for Suicide Ideation ;Snaith-Hamilton Pleasure Scale ;Magnetic resonance imaging; | — |
Countries
China
Contacts
Public ContactZhang Bin
Tianjin Anding Hospital
Outcome results
None listed