respiratory disease
Conditions
Interventions
Low suction pressure group:The patients in the control group were treated with hemostatic forceps to clamp the negative pressure drainage catheter prior to flushing. They then disconnected the cathete
Medium suction pressure group:Initially, the patients in this group had the active heating and humidifying device of the ventilator activated, with the inlet of the bridge tube connected to the Y-shap
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
14 Years to 89 Years
Inclusion criteria
Inclusion criteria: The diagnosis of common diseases in all patients included multiple trauma, septic shock, various post-operative, various types of poisoning, multiple organ failure, severe obstetric, cardiopulmonary resuscitation, etc. All family members were informed of the purpose and process of this study and obtained informed consent. All met the following inclusion criteria : 1. patients who were mechanically ventilated in the ICU of our hospital; 2. mechanical ventilation for more than 48 hours; 3. age >= 18 years; 4. ventilator mode set to pressure-controlled ventilation (PCV); 5. Richmond Agitation Sedation Scale score ranging from 0 to -2.
Exclusion criteria
Exclusion criteria: 1. airway mucosal injury or bleeding, unobstructed suction catheter, severe hypoxemia and/or carbon dioxide retention prior to IASS; 2. sudden changes in condition during drainage (procedure termination under physician supervision); 3. refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of the occult blood test;Blockage rate of the drainage catheter;The viscosity of subglottic secretions;Incidence of ventilator-associated pneumonia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Exhaled tidal volume;Cuff pressure;Suction pressure;Sputum suctioning effect score; | — |
Countries
China
Contacts
Public ContactWeiquan Liu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed