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Clinical research on LY6E as a biomarker of infection and inflammation

Clinical research on LY6E as a biomarker of infection and inflammation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106490
Enrollment
Unknown
Registered
2025-07-24
Start date
2025-07-25
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Gold Standard:Infectious diseases: Diagnosed by culture, microscopy, histology, PCR, antigen/antibody tests, or MALDI-TOF.
Index test:LY6E

Sponsors

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Age: No limit. 2. Gender: No restrictions; 3.Patients with pathogenic microbial infections, sepsis, and autoimmune diseases (such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, and autoimmune diseases) who visited multiple departments including the Department of Infectious Diseases, Department of Oncology, and Department of Rheumatology and Immunology at multiple centers including Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University (the leading unit) from October 2023 to May 2025 Patients with chronic hepatitis, tumor fever, organ transplant recipients, and those with tissue damage caused by surgery, as well as healthy individuals who have undergone physical examinations at multiple centers including Sir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine.

Exclusion criteria

Exclusion criteria: 1.Patients with unclear pathogen detection results; 2.Those with incomplete clinical data; 3.Clinical samples that do not meet the research requirements.

Design outcomes

Primary

MeasureTime frame
level of LY6E in blood is significantly associated with infection;

Countries

China

Contacts

Public ContactMa Yilei

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University

yilei1986@163.com+86 18368143891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026