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Comparison of Anticoagulation Efficacy Ionized Calcium vs. Post-filter Ionized Calcium During Regional Citrate Anticoagulation in Continuous Renal Replacement Therapy - A Single-Center Randomized Controlled Trial

Comparison of Anticoagulation Efficacy: Effluent Ionized Calcium vs. Post-filter Ionized Calcium During Regional Citrate Anticoagulation in Continuous Renal Replacement Therapy - A Single-Center Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106487
Enrollment
Unknown
Registered
2025-07-24
Start date
2025-07-25
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Continuous renal replacement therapy

Interventions

Study Group:none
Control Group :none

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients receiving CRRT with regional citrate anticoagulation (RCA) in all departments of West China Hospital, Sichuan University; (2) Aged between 18 and 80 years; (3) Vascular access limited to femoral vein, jugular vein, or cuffed (CUFF) tunneled catheters; (4) Informed consent voluntarily signed by the patient or their legal representative.

Exclusion criteria

Exclusion criteria: (1) CRRT duration = 2 anticoagulants during CRRT; (3) Pregnancy; (4) CRRT without regional citrate anticoagulation (RCA); (5) Concurrent use of >= 2 blood purification modalities; (6) Inability to comply with the study due to psychiatric disorders or other reasons.

Design outcomes

Primary

MeasureTime frame
Ultrafiltrate Ionized Calcium Concentration vs. Post-Filter Ionized Calcium Concentration;—

Countries

China

Contacts

Public ContactLing Zhang

West China Hospital, Sichuan University

zhangling_crrt@163.com+86 189 8060 1985

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026