None listed
Conditions
Interventions
Tobacco-free oral tobacco group:Five days use of tobacco-free oral tobacco
e-cigarette group:5-day use of e-cigarette
Heated tobacco product group:5-day use of heated tobacco product.
Cigarette group:5-day use of cigarette
Oral tobacco group:5-day use of oral tobacco
Smoking cessation group:Quit smoking for five days.
Sponsors
Shanghai Institute for Biomedical and Pharmaceutical Technologies
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 20 and 55 years old; 2.Cigarette consumers; 3.Have not taken smoking cessation products/drugs (such as smoking cessation candies, smoking cessation patches, smoking cessation medications, etc.) in the week before participating in the study; 4.With a body mass index (BMI) (weight (kg)/height (m)²) between 18.5 and 27.9 (men with a weight of not less than 52 kg and women with a weight of not less than 45 kg); 5.Understand the information provided in the research project and can make their own decisions on whether to participate in the study; 6.Those who voluntarily participate in the study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Those suffering from acute/chronic respiratory system diseases; 2.Those with malignant tumors; 3.Those suffering from acute/chronic digestive system diseases; 4.Those with acute/chronic liver/kidney diseases; 5.Those with cardiovascular diseases or diabetes; 6.Those with immune system diseases or allergic diseases; 7.Those with mental illnesses; 8.Women who are menstruating, breastfeeding or pregnant; 9.Those who have participated in other clinical trials in the last three months; 10.Those who cannot or are unwilling to provide the informed consent form; 11.Subjects with poor compliance; 12.Those without legal capacity or with restricted legal capacity; 13.Any other situations that the researcher deems inappropriate for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in smoking behavior parameters;Serum/plasma/urine concentrations of the selected biomarkers; | — |
Countries
China
Contacts
Public ContactYan Che
Shanghai Institute for Biomedical and Pharmaceutical Technologies
Outcome results
None listed