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Effects of Intraoperative Thermoregulation on Early Postoperative Pulmonary Complications and Inflammatory Markers in Elderly Patients Undergoing Hip and Knee Arthroplasty

Effects of Intraoperative Thermoregulation on Early Postoperative Pulmonary Complications and Inflammatory Markers in Elderly Patients Undergoing Hip and Knee Arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106484
Enrollment
Unknown
Registered
2025-07-24
Start date
2025-08-10
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Hip/Knee Arthroplasty

Interventions

The Low Temperature Group (L Group):During the operation, an active warming device was used to maintain the patients body temperature at 36?. The remaining nursing measures and anesthesia methods were
The Middle Temperature Group (L Group):During the operation, an active warming device was used to maintain the patients body temperature at 36.5?. The remaining nursing measures and anesthesia methods
The High Temperature Group (L Group):During the operation, an active warming device was used to maintain the patients body temperature at 37?. The remaining nursing measures and anesthesia methods wer

Sponsors

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing elective total hip and knee arthroplasty with endotracheal intubation under general anesthesia. (2) Aged >=60 years and <=80 years. (3) Preoperative axillary temperature of 36?-37.2?. (4) Preoperative Lus score of 0 points. (5) ASA physical status classification of Class I-III. (6) Duration of anesthesia between 1 hour and 3 hours. (7) Body mass index (BMI) between 18.5 and 30. (8) Willing to participate in this study and having signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with preoperative cardiovascular or pulmonary diseases. (2) Patients with preoperative hypoproteinemia. (3) Patients with preoperative white blood cell count >=12×10^9/L. (4) Patients with rheumatic diseases. (5) Patients with diabetes mellitus. (6) Patients undergoing dialysis. (7) Patients with BMI 30. (8) Patients with psychiatric disorders or cognitive dysfunction, who are unable to sign the informed consent form and cooperate with the study.

Design outcomes

Primary

MeasureTime frame
Lung Ultrasound Score;The level of serum interleukin-6 (IL-6);

Secondary

MeasureTime frame
Cough and sputum production incidence;Incidence of fever;

Countries

China

Contacts

Public ContactLi Sulian

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University

414776011@qq.com+86 150 8207 0966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026