Chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1.Patients diagnosed with periodontitis based on the following conditions according to the 2018 criteria: 1) Loss of adjacent surface attachment was detected in two non-adjacent teeth (attachment loss, AL); 2) 3 mm of AL was detected on the buccal or lingual side of 2 teeth, with periodontal bag depth (probing depth, PD)>= 3mm. Non-periodontitis-caused AL should be excluded. 2.Additionally, a reassessment at 4 to 6 weeks after basic periodontal treatment revealed at least two nonadjacent PD >=4 mm and AL >=4mm with probing hemorrhage in the left and right quadrants of the mouth. 3. The age range of patients was >=25 years and <=60years.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1.Systemic diseases (such as diabetes, cardiovascular disease, etc.) that affect the progression or efficacy of periodontitis; 2. Women during pregnancy and lactation; 3. Smokers; 4. Use of antibiotics within 3 months; 5. Affected teeth with periodontal surgery; 6. Affected teeth with significant occlusal trauma; 7. Affected teeth with combined periodontal-pulpal involvement; 8. The site of third molar resistance in the secon
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing Depth;Loss of attachment;Bleeding index ;Porphyromonas gingivals;Interleukin 6 (IL-6);Tumor necrosis factor a;C-reactive protein; | — |
Countries
China
Contacts
Hospital of Stomatology Hebei Medical University