Skip to content

Optimization of anesthesia in thyroid surgery: a single center randomized controlled trial clinical study protocol

Optimization of anesthesia in thyroid surgery: a single center randomized controlled trial clinical study protocol

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106463
Enrollment
Unknown
Registered
2025-07-24
Start date
2024-12-10
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Group C:Dexamethasone 10mg+traditional intubation method
Group D1:Dexamethasone 10mg+bronchoscope adjustment
Group D2:Dexamethasone 20mg+bronchoscope adjustment

Sponsors

Yunnan First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Individuals who voluntarily sign an informed consent form. 2. Individuals aged between 18 and 50 years old. 3. Individuals classified as American Society of Anesthesiologists (ASA) Class I or II. 4. Patients scheduled for elective open thyroid surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with upper respiratory tract infections within 1 month prior to surgery and those with respiratory system diseases (chronic obstructive pulmonary disease, hypoxemia, asthma, etc.); 2. Patients with sore throat or hoarseness of voice prior to surgery; 3. Patients with anatomical changes in the face, neck, and upper respiratory tract and anticipated difficult airway; 4. Patients with hypertension and severe cardiovascular and cerebrovascular diseases (carotid plaque and stenosis, intracranial hematoma, subarachnoid hemorrhage); 5. Patients with peripheral circulatory disorders and intracranial hypertension; 6. Patients with diabetes or hyperglycemia; 7. Surgery duration exceeding 3 hours; 8. Patients with hematoma formation, nerve injury, or thyroid storm postoperatively; 9. Patients with severe coughing and restlessness before extubation postoperatively.

Design outcomes

Primary

MeasureTime frame
Throat pain score;Postoperative nausea and vomiting;The difference in length (?L) from the tip of the catheter to the carina before and after head position change;The distance from the tracheal tube to the corner of the mouth;Anesthesia satisfaction;

Secondary

MeasureTime frame
MAP;Heart Rates;Coughing during extubation;Sputum with blood streaks during extubation;

Countries

China

Contacts

Public ContactJin Hua

Yunnan First People's Hospital

Jinhuakm@qq.com+86 138 8866 8869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026