Salivary gland tumors and odontogenic tumors
Conditions
Interventions
Gold Standard:Gold standard for fusion genes: Using FISH test results as the gold standard
Gold standard for gene mutations: Using Sanger sequencing results as the gold standard.
Index test:Next-generation sequencing (NGS)-based multi-gene detection kits, designed for fusion gene detection in salivary gland tumors, mutation gene detection in salivary gland tumors, and mutation
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 90 Years
Inclusion criteria
Inclusion criteria: 1. Both male and female patients; 2. Age range: 0 =1cm, with sufficient residual tumor samples remaining after routine pathological diagnosis to simultaneously conduct two sets of tests (single-gene testing and panel multi-gene kit testing); 5. Tumor component in sections should exceed 50%.
Exclusion criteria
Exclusion criteria: 1. Tumor necrosis exceeds 30% in the slice; 2. Puncture specimen; 3. Poor quality of extracted DNA/RNA (concentration <10ng/ul and OD value 260/280 <1.8); 4. Library construction failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Area Under ROC Curve; | — |
Countries
China
Contacts
Public ContactJiang Li
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed