Acute Retinal Necrosis
Conditions
Interventions
Medical Treatment Group :intravitreal and systemic antiviral drug therapy
prophylactic vitrectomy group:undergoing elective vitretomy, besides intravitreal and systemic antiviral drug therapy
vitretomy group :undergoing emergency vitretomy, besides intravitreal and systemic antiviral drug therapy
Sponsors
The First Affiliated Hospital of USTC
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1)The patients underwent examinations, including slit lamp microscope, indirect ophthalmoscope, ocular B-ultrasound and intraocular fluid detection, and was diagnosed as acute retinal necrosis, according to Classification Criteria for Acute Retinal Necrosis Syndrome published by Standardization of Uveitis Nomenclature (SUN) Working Group in 2021. 2) Good compliance, able to cooperate and complete relevant examinations and treatments.
Exclusion criteria
Exclusion criteria: 1)History of ocular surgery or trauma, including cataract surgery within 6 months; 2) With other systemic diseases, unable to cooperate and tolerate examination and treatment; 3) No intraocular fluid test or two intraocular fluid PCR tests were negative; 4) Failed to complete antiviral and related treatment;5)Patients whose affected eye meets the criteria for vitrectomy but refuse to undergo the surgical procedure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best-corrected visual acuity (BCVA) ;Retinal reattachment status; | — |
Secondary
| Measure | Time frame |
|---|---|
| viral load of intraocular fluid; | — |
Countries
China
Contacts
Public ContactGu Yonghao
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed