None listed
Conditions
Interventions
The fluid replacement group guided by the axillary vein collapse index:Fluid replacement guided by the axillary vein collapse index
The conventional fluid replacement group:Use conventional fluid replacement at a rate of 8 ml/kg/h
Sponsors
The First Hospital of Shanxi Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 65 or above, scheduled for laparoscopic cholecystectomy under general anesthesia; 2. ASA score ranging from 1 to 2; 3. Surgery duration of 2 to 6 hours; 4. No cognitive impairment before the operation, or if there is a mental disorder, but it has been well controlled for the past 6 months and the cognitive function is not impaired; 5. No damage to important organs such as heart, brain, or kidneys; 6. The patient and their family have agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with mental or neurological disorders; 2. Baseline mean arterial pressure (MAP) less than 65 mmHg; 3. Congestive heart failure with left ventricular ejection fraction less than 40%, acute or chronic renal failure, or other severe heart, lung, kidney or liver diseases; 4. Patients with coagulation disorders; 5. Patients who refuse to continue observation and withdraw from the experiment on their own; 6. Patients whose studies must be terminated due to significant hemodynamic fluctuations or severe anaphylactic shock during the perioperative period; 7. Patients lost to follow-up after discharge due to force majeure. 8. Anesthetic drug allergy sufferers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of delirium during the recovery period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function score;VAS pain score;The first time to get out of bed for activities;The first time of anal exhaust;hospital stays;Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactYang Ling
Department of Anesthesiology, The First Hospital of Shanxi Medical University
Outcome results
None listed