Myopic Choroidal Neovascularization
Conditions
Interventions
Myopic choroidal neovascularization:None
Simple high myopia:None
Sponsors
Eye Hospital China Academy of Chinese Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: ?1.Case group inclusion criteria:?? (1) Meeting the diagnostic criteria for myopic choroidal neovascularization(mCNV); (2) Aged 18–60 years; (3) Relatively clear refractive media without affecting fundus examination; (4) Voluntary participation with signed informed consent. 2.??Control group inclusion criteria:?? (1) Meeting the diagnostic criteria for simple high myopia; (2) Aged 18–60 years; (3) No other ocular diseases except refractive error; (4) Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Case group exclusion criteria:?? (1) History of ocular trauma or eye surgery; (2) Presence of tractional myopic maculopathy, including vitreomacular traction, macular schisis, macular hole, or retinal detachment; (3) Other ocular diseases that may cause CNV (e.g., AMD, diabetic retinopathy, central exudative chorioretinopathy); (4) Other vision-impairing ocular conditions (e.g., glaucoma, central serous chorioretinopathy, retinal vascular diseases, uveitis); (5) Severe cardiovascular/cerebrovascular diseases or psychiatric disorders; (6) Pregnant or lactating women. ??2.Control group exclusion criteria:?? (1) History of ocular trauma or eye surgery; (2) Intraocular pressure =21 mmHg; (3) Visual field defects; (4) High myopia complications (e.g., retinoschisis, CNV); (5) Severe cardiovascular/cerebrovascular diseases or psychiatric disorders; (6) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene;Constitution of Traditional Chinese Medicine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Uncorrected distance visual acuity;Best corrected distance visual acuity;Intraocular pressure;Equivalent spherical lens degree;Eye axis;Corneal curvature;Central macular thickness;Subfoveal choroidal thickness;Superficial capillary plexus vessel density;Deep capillary plexus vascular density;Choroidal capillary plexus vascular density;The area of the foveal avascular zone;Environmental factor indicators;Anxiety and depression scale score;Quality of life scale score; | — |
Countries
China
Contacts
Public ContactKang Zefeng
Eye Hospital China Academy of Chinese Medical Science
Outcome results
None listed