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Effect of cryomodulation of bone cement viscosity on the degree of cement dispersion and clinical outcome after percutaneous vertebroplasty(PKP)

The influence of bone cement dispersion effect on the clinical efficacy of osteoporotic vertebral compression fractures

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106408
Enrollment
Unknown
Registered
2025-07-23
Start date
2025-07-25
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporotic vertebral compression fractures

Interventions

Low Temperature Group(LT group):NA
Normal Saline Group(NS group):NA
Room Temperature Group(RT group):NA

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
51 Years to 91 Years

Inclusion criteria

Inclusion criteria: 1. Bone mineral density (BMD-T) T value =-2.5; 2. Single-level thoracic or lumbar spine fracture and first treatment with PKP surgery 3. Not accompanied by radiating pain, numbness, weakness or other nerve compression symptoms of the lower extremities 4. Preoperative MRI confirmed the diagnosis of fresh compression fracture. 5. Follow-up time is more than 24 months.

Exclusion criteria

Exclusion criteria: 1. Pathological fractures caused by tumors or infections; 2. The posterior edge of the fractured vertebral body protrudes into the spinal canal and obviously compresses the dural sac, or obvious structural damage to the posterior column 3. Patients with severe systemic diseases who cannot tolerate surgery; 4. Patients with incomplete data or missed diagnosis.

Design outcomes

Primary

MeasureTime frame
Bone Cement Dispersion Score;Postoperative vertebral re-fracture rate;

Countries

China

Contacts

Public ContactHu Feng

The Affiliated Hospital of Xuzhou Medical University

646080535@qq.com+86 176 8102 6690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026