None
Conditions
Interventions
Dexmedetomidine group (group D):1.0µg/kg Dex was administered, dexmedetomidine was diluted to 2ml with normal saline, and 1ml was sprayed on each side of the nasal cavity 10 minutes before surgery
Blank control group (group C):10 minutes before surgery, group C was given the same amount of saline nasal spray
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Study participants undergoing painless rigid tracheoscopy; 2. Age 18 - 75 years old, gender is not limited; 3. Body mass index (BMI) 18~30 kg/m^2; 4. ASA Grading I- III; 5. Have a clear understanding and voluntarily participate in the study, and have the informed consent form signed by themselves or their family members.
Exclusion criteria
Exclusion criteria: 1. History of dexmedetomidine allergy; 2. Previous heart failure or arrhythmia; 3. History of mental illness; 4. History of reflux esophagitis; History of chronic pharyngitis; Preoperative presence of sore throat, hoarseness, dysphagia, bleeding, or use of anticoagulants; high risk of reflux aspiration; History of oral and pharyngeal surgery or upper respiratory tract infection within 2 weeks before surgery; 5. Abnormal liver and kidney function; 6. Refusal to sign the informed consent form; 7. Recent nasal injury; 8. Has participated in other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of postoperative sore throat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative, intraoperative and postoperative hemodynamic changes were observed;The amount of anesthetics used;The incidence of postoperative nausea and vomiting;Postoperative hoarseness and cough were observed;Quality of postoperative recovery QoR-15 score;Ramsay score in the recovery room;Participant satisfaction and operator satisfaction;Rigid bronchoscope placement time, placement times and indwelling time;; | — |
Countries
China
Contacts
Public ContactLianyi Zhang
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed