Depressive emotion
Conditions
Interventions
Sponsors
Peking University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.For recruiting healthy control group subjects, the following conditions must be met simultaneously: (1) Aged between 18 and 55 (try to maintain a balanced gender ratio); (2) The individual is in good physical and mental health, with scores on the depression scales (SDS/HAMD) below the threshold for depressive mood, and no history of mental illnesses such as anxiety or bipolar disorder. Cognitive function is confirmed to be normal through a brief mental status examination (MMSE). There is no past history or family history of physical diseases; (3) Able to use devices such as smartphones and smartwatches; (4) Volunteer to participate in this study and be able to provide informed consent; (5) Not having taken psychotropic drugs or medications for hypertension and heart disease for a long time; (6) Not participating in other similar research projects simultaneously. 2.For recruiting subjects with depressive mood, the following conditions must be met simultaneously: (1) Aged between 18 and 55 (with a balanced gender ratio as much as possible); (2) People initially diagnosed with depressive mood at the outpatient clinic of Peking University Sixth Hospital: They are screened using self-rating depression scales (such as SDS) or observer-rated scales (such as HAMD), with scores reaching the threshold for depressive mood (usually SDS = 53 or HAMD = 7). After evaluation according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) or the International Classification of Diseases (ICD-11), they do not meet the diagnostic criteria for depressive disorder, but are in a state of depressive mood; (3) They had not taken any psychotropic medication or undergone any psychological treatment in the two weeks prior to participating in the study; (4) Able to use devices such as smartphones and smartwatches; (5) The patient voluntarily participates in this study, and informed consent is provided by the patient or their legal guardian based on the patient's capacity for civil conduct; (6) Not taking long-term medication for psychiatric disorders, hypertension, heart disease, or other medications; (7) Not participating in other similar research projects simultaneously. 3.For recruiting subjects with depressive disorders, the following conditions must be met simultaneously: (1) Aged between 18 and 55 (with a balanced gender ratio as much as possible); (2) Patients initially diagnosed with depressive disorders at the outpatient clinic of Peking University Sixth Hospital: Those who meet the diagnostic criteria for depressive disorders as outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) or the International Classification of Diseases (ICD-11) (such as core symptoms like persistent low mood and diminished interest for more than 2 weeks, accompanied by at least 4 other symptoms), and are confirmed by a psychiatrist to be in a depressive episode (not fully remitted); (3) Have not taken any psychotropic medication or undergone any psychological treatment in the 2 weeks prior to participating in the study; (4) Able to use devices such as smartphones and smartwatches; (5) The patient voluntarily participates in this study, and informed consent is provided by the patient or their legal guardian based on the patient's capacity for civil conduct; (6) Not taking long-term medication for psychiatric disorders, hypertension, heart disease, or other medications; (7) Not participating in other similar research projects simultaneously
Exclusion criteria
Exclusion criteria: 1.Three sets of common exclusion criteria: (1) Suffering from severe mental illnesses, such as schizophrenia, acute episode of bipolar disorder, severe cognitive impairment, etc; (2) History of abuse of alcohol, drugs, or other psychoactive substances; (3)Individuals who are allergic to the materials of wearable devices, suffer from severe skin diseases, or have implanted electronic devices (such as pacemakers); (4) Women who are pregnant or breastfeeding; After conducting an anxiety scale assessment (such as the Generalized Anxiety Disorder 7-item Scale, GAD-7), individuals in a high anxiety state (e.g., GAD-7 score = 10). 2.Additional exclusion criteria for the depressive disorder group: (1) High risk of suicide, with a clear recent suicide plan or behavior as determined through clinical assessment; (2) Comorbid with other severe mental disorders, such as those who simultaneously meet the diagnosis of anxiety disorders, eating disorders, etc., and whose symptoms seriously affect data collection. 3.Additional exclusion criteria for the healthy control group: Having experienced major stressful events (such as the death of a loved one or a serious illness) in the past six months that may have triggered transient depressive mood.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physiological behavior data (heart rate, stress, body temperature, blood oxygen saturation, and sleep status); | — |
Countries
China
Contacts
Public ContactSun Xinying
Peking University
Outcome results
None listed