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The experimental study on the improvement of antihypertensive drug sensitivity in patients with refractory hypertension by intermittent fasting

The experimental study on the improvement of antihypertensive drug sensitivity in patients with refractory hypertension by intermittent fasting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106370
Enrollment
Unknown
Registered
2025-07-23
Start date
2022-10-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory hypertension

Interventions

Experimental group:intermittent fasting for one month

Sponsors

The Cardiology Department of the First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria for the refractory hypertension group are in accordance with the 2020 edition of the Chinese Guidelines for the Diagnosis and Treatment of Refractory Hypertension: on the basis of lifestyle improvement, the blood pressure cannot be controlled below 140/90mmHg with three or more antihypertensive drugs (including one diuretic) in sufficient doses and with reasonable combinations

Exclusion criteria

Exclusion criteria: 1. History of malignant tumors, severe systemic infectious diseases, hematological diseases and organ transplantation; 2. Severe heart failure, hyperthyroidism, hypothyroidism, etc.; 3. Severe liver and kidney dysfunction, etc.

Design outcomes

Primary

MeasureTime frame
Blood pressure ;Intestinal flora;—

Countries

China

Contacts

Public ContactYongtai Gong

The first Afiliated Hospital of Harbin Medical University

gongth@126.com+86 159 4518 1294

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026