Sepsis
Conditions
Interventions
Plains Group?:None
Plateau group?:None
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Plateau group one: 1) meet the diagnostic criteria for sepsis 3.0 developed by the Sociey of Critical Care Medicine (SCCM)/European Society of Critical Care Medicine (ESICM); 2) Age>= 18 years old, Han nationality, gender is not limited; 3) Diagnosis of sepsis within 48 hours of admission; 4) The long-term (time>3 years) of the patient's (subject's) place of residence is >= 3000m above sea level;5) Agree to take blood samples for relevant omics testing, and the patient and his family members sign the informed consent form; 2.Plateau Group two: 1) Age>= 18 years old, Han nationality, gender is not limited;2) sepsis or other chronic diseases were not diagnosed at the time of sampling; 3) Agree to take blood samples for relevant omics testing, and the patient and his family members sign the informed consent form. 3.Plains group one: 1)met the diagnostic criteria for sepsis 3.0 developed by the Sociey of Critical Care Medicine (SCCM)/European Society of Critical Care Medicine (ESICM); 2) Age>= 18 years old, Han nationality, gender is not limited; 3) Diagnosis of sepsis within 48 hours of admission; 4) The long-term (time>3 years) of the patient's (subject's) place of residence is = 18 years old, Han nationality, gender is not limited; 2) sepsis or other chronic diseases were not diagnosed at the time of sampling; 3) Agree to take blood samples for relevant omics testing, and the patient and his family members sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Age< 18 years old; 2) Hospitalization is less than 24 hours; 3) patients with shock with an unclear diagnosis; 4) pregnant and lactating women; 5) end-stage malignant tumor; 6) Inability to obtain informed consent or authorization;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| APACHEII score;APTT;Hb;TT;Total bilirubin;Na;Fib;Fasting blood glucose;weight;PT;RBC;IL-6;Abdominal ultrasound;MONO;CRP;Lymphocyte subsets;Thoracoabdominal CT;Prealbumin;AST;ALT;WBC;height;Regular electrocardiogram;BMI;Direct bilirubin;Urea nitrogen;SOFA score;NEU%;calcium;creatinine;Blood gas analysis;PLT;Indirect bilirubin;PCT;K;Triglycerides;cholesterol;NEU;Albumin;LYM;cl; | — |
Countries
China
Contacts
Public ContactYin Changlin
The First Affiliated Hospital of Army Medical University
Outcome results
None listed