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The impact of ultrasound-guided external oblique intercostal block with liposomal bupivacaine on the quality of postoperative recovery in patients undergoing laparoscopic cholecystectomy

The impact of ultrasound-guided external oblique intercostal block with liposomal bupivacaine on the quality of postoperative recovery in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106353
Enrollment
Unknown
Registered
2025-07-22
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Group R:After induction of general anesthesia and endotracheal intubation, bilateral external oblique intercostal plane blocks were performed under ultrasound guidance. Each sie received 20 ml of 0.4
Group LB:After induction of general anesthesia and endotracheal intubation, bilateral external oblique intercostal plane blocks were performed under ultrasound guidance. Each side received 20 ml of l

Sponsors

Shunde Xinrongqi Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged 18–65 years ; 2. Classified as ASAI-II; 3. Selective laparoscopic cholecystectomy; 4.Agree to participate in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. History of upper abdominal surgery; 2. Refusal to undergo nerve block; 3. Pregnant or lactating women; 4. Coagulation dysfunction; 5. Infection or tumor at the puncture site; 6. History of allergy to the drugs in this study; 7. History of gastrointestinal ulcers; 8. Liver or kidney insufficiency; 9. Long-term use of analgesic drugs; 10. Inability to communicate with follow-up personnel.

Design outcomes

Primary

MeasureTime frame
QoR-15 score ;

Secondary

MeasureTime frame
VAS score;Number of analgesic rescue administration.; Total dose of tramadol used within 72 hours postoperatively.;The time elapsed from the end of surgery to the first request for analgesic rescue.;The level of sensory regression on the abdominal wall;The time of first flatus post-surgery; The time of first ambulation out of bed post-surgery;Satisfaction of patients;

Countries

China

Contacts

Public ContactLujun Cen

Shunde Xinrongqi Hospital

271542110@qq.com+86 177 8684 0786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026