Insufficient bone mass in dental implant alveolar bone
Conditions
Sponsors
The Affiliated Stomatological Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age range of 18-70 years old (including upper and lower limits), gender is not limited; 2. Patients with maxillary posterior dental arch defects that have been missing for at least 3 months and require implant repair; 3. Perform bone augmentation and staged implant implantation using the maxillary sinus lift technique with a lateral window opening; 4. The remaining radiological height of the alveolar ridge is less than 4 mm, and the width of the alveolar ridge is >= 6 mm; 5. At least one adjacent tooth should be used as a reference, and the adjacent tooth should not have a metal post core crown restoration; 6. The subjects voluntarily sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients who have previously had bone powder filled in the surgical tooth position; 2. Patients with acute maxillary sinus infection or maxillary sinus cyst; 3. Untreated periodontitis patients, acute periapical periodontitis, periapical cysts, and/or patients with advanced periodontal disease need to be excluded; 4. Patients with poor oral environment who cannot maintain good oral hygiene care; 5. Patients with a history of head and neck radiation therapy or currently undergoing radiation therapy; 6. Patients with poorly controlled diabetes (fasting blood glucose value exceeds 2 times the upper limit of normal value), and patients with poorly controlled hypertension (systolic blood pressure = 160 mmHg and/or diastolic blood pressure >= 100 mmHg); 7. Patients with abnormal liver and kidney function (ALT and AST values exceeding 1.5 times the upper limit of normal, or creatinine exceeding normal); 8. Patients with bone metabolism disorders (such as osteoporosis, abnormal osteoarthritis, etc.), or those who have taken drugs or products that can significantly affect bone metabolism (such as steroids, bisphosphonates, etc.) within the past 3 months before enrollment; 9. Patients with severe heart, liver, lung, kidney and other important organ diseases or severe blood, immune, endocrine system diseases; 10. Patients who smoke heavily (>= 10 cigarettes/day); 11. Pregnant and intending pregnant women of childbearing age or breastfeeding women; Male patients whose spouse intends to conceive; 12. Patients with severe mental illness; 13. The patient has participated in or is currently participating in clinical trials of other drugs or devices within the past 3 months; 14. Patients with poor compliance or those deemed unsuitable for inclusion by researchers;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative analysis of micro computed tomography (Micro CT);Changes in vertical bone height within the maxillary sinus at 180 ± 14 days after surgery compared to immediately after surgery;Organizational Metrology Analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of wound healing status;Incidence of postoperative complications; | — |
Countries
China
Contacts
Public ContactShen Ming
The Affiliated Stomatological Hospital of Nanjing Medical University
Outcome results
None listed