Colorectal surgery,pain,inflammatory reaction
Conditions
Interventions
Sufentanil combined with ropivacaine sacral block group:Intrasacral injection of sufentanil combined with ropivacaine
Nabufine combined with ropivacaine sacral block group:Intrasacral injection of nabufine combined with ropivacaine
Ropivacaine sacral block group:Intrasacral injection of ropivacaine
Sponsors
Hefei First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients planning to undergo colorectal surgery; 2.Age range: 18-65 years old; 3.ASA class I-II; 4.The BMI index is 18.5-27.9; 5.The patient is able to communicate normally, and both the patient and their family members provide informed consent and sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Merge with serious diseases of important system organs such as the heart and brain; 2.History of spinal deformities, spinal lesions, or spinal surgery; 3.Abnormal coagulation function prevents sacral block anesthesia; 4.Allergic to these medication;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthesia onset time and duration;Interleukin-6 (IL-6), tumor necrosis factor - a (TNF - a), serum C-reactive protein (CRP);anesthetic effect;Anesthesia duration time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure; | — |
Countries
China
Contacts
Public ContactYang Heng
Hefei First People's Hospital
Outcome results
None listed