peri-implantitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18-70 years old; 2. No history of severe periodontitis and good oral hygiene; 3. Healthy patients predicted to be at high risk for peri-implantitis by integrated model.
Exclusion criteria
Exclusion criteria: 1. Patients with systemic contraindications for implant surgery and severe liver, kidney and heart insufficiency; 2. Occlusal deformities or temporomandibular joint disorders; 3. severe periodontal disease; 4. The patient has systemic diseases that may affect osseointegration/tissue healing, such as uncontrolled diabetes (fasting blood glucose greater than 11.1mmol/L), systemic or local bone diseases such as osseointegration, osteitis, bone tumors; 5. Serious hematological diseases, such as leukemia or other hemorrhagic diseases (such as prothrombin time prolongation of more than 6 seconds); 6. Patients with cardiovascular and cerebrovascular diseases who cannot tolerate surgery; 7. Patients are taking drugs that may affect bone metabolism / tissue healing (diphosphate drugs or high-dose adrenocortical hormones); 8. Radiation Osteomyelitis; 9. Specific allergic constitution; 10. Bruxism; 11. Pregnant or lactating women; 12. Unwilling to participate in clinical research or unable to return to the clinic on time; 13. Other cases that the investigator judges cannot participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gingival index;probing depth;marginal bone loss;modified sulcus bleeding index; | — |
Countries
China
Contacts
School of Stomatology, Air Force Military Medical University