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To explore the effect of supplementing probiotics before enterostomy reduction on the intestinal colonizing flora of rectal cancer patients

To explore the effect of supplementing probiotics before enterostomy reduction on the intestinal colonizing flora of rectal cancer patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106283
Enrollment
Unknown
Registered
2025-07-21
Start date
2025-07-21
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Control group:No probiotic supplementation before surgery
Experimental group 1:Oral administration of Bifidobacterium brevis
Experimental group 2:Infusion of a mixture of Bifidobacterium yeast and normal saline from the distal end of the colostomy tube
Experimental group 3:Take oral Blasilla yeast and infuse a mixture of Blasilla yeast and normal saline from the distal end of the colostomy.

Sponsors

The First Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pathological diagnosis of colon cancer and/or rectal cancer; 2. Patients who have undergone temporary enterostomy; 3. Patients who can collect complete clinical data; 4. No contraindications to enterostomy reduction; 5. Patients voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with rectal cancer with clear pathological diagnosis confirming distant metastasis; 2. Patients with colorectal metastasis whose primary disease is other malignant tumors.

Design outcomes

Primary

MeasureTime frame
Transit enteritis condition;

Secondary

MeasureTime frame
Intestinal obstruction situation;Infection status;Postoperative hospital stay duration;

Countries

China

Contacts

Public ContactYang Jun

The First Affiliated Hospital of Kunming Medical University

yangjun6@kmmu.edu.cn+86 159 1168 8980

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026