Patients with hematologic malignancies who have undergone hematopoietic stem cell transplantation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18 years old<= age <= 70 years old, gender is not limited; 2. Patients diagnosed with the need for hematopoietic stem cell transplantation (HSCT), including allogeneic and autologous hematopoietic stem cell transplantation; 3. Have completed pre-transplant evaluation prior to transplantation and are candidates for HSCT; 4. Ability to complete the filling of the scale questionnaire; 5. Able to accept follow-up and willing to cooperate with the investigator to complete the study requirements; 6. Signed informed consent;
Exclusion criteria
Exclusion criteria: 1. Comorbid severe psychiatric disorder or cognitive dysfunction that precludes accurate assessment of mood, motor, and sleep status; 2. Patients who have received prior hematopoietic stem cell transplantation or other significant therapeutic interventions that may affect the study data; 3. Presence of serious complications (e.g., organ failure, active infection) prior to transplantation that may affect the evaluation of transplant outcomes; 4. Pregnant or lactating females; 5. Those who are expected to be at higher risk of loss to follow-up due to relocation or other reasons during the follow-up period; 6. Special circumstances that other investigators consider inappropriate to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute severe graft-versus-host disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to neutrophil and platelet engraftment;Overall Survival Rate;Quality of life;Recurrence rate;Incidence of non-severe acute GVHD and chronic GVHD; | — |
Countries
China
Contacts
The Second Affiliated Hospital of the Army Medical University