post-operative pain
Conditions
Interventions
The Bupivacaine Hydrochloride Group:Administer bupivacaine hydrochloride for erector spinae plane block.
The Liposomal Bupivacaine Group:Administer liposomal bupivacaine for erector spinae plane block.
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The age ranges from 18 to 80 years old (including 18 years old and 80 years old, regardless of gender). 2. The American Society of Anesthesiologists (ASA) physical status classification is grade I - III. 3. The surgical scope does not exceed three lumbar spine segments. 4. The body mass index (BMI) is less than 31 kg/m². 5. Able to understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with infections at the puncture points where block analgesia is planned. 2. Patients with abnormal coagulation function. 3. Patients with liver insufficiency. 4. Patients with kidney insufficiency. 5. Patients who are allergic to the drugs in the research protocol. 6. Patients with mental disorders. 7. Patients who have been taking opioid analgesic drugs for a long time (the duration of taking drugs is no less than one month). 8. Patients undergoing a second posterior lumbar spine surgery. 9. Patients who have participated in other drug-related clinical trials within the past 30 days. 10. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total usage amount of opioids within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects of erector spinae plane block and analgesic medications;Opioid Dosage;length of hospital stay;Post - operative Recovery Quality: QOR - 15 Score;NRS Score at Rest and During Activity; | — |
Countries
China
Contacts
Public ContactZhang Qingfen
Peking University People's Hospital
Outcome results
None listed