Gynecologic laparoscopic total hysterectomy
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18~65 years old; 2. ASA grading I~III. 3. BMI 18~30 kg/m^2; 4. Intended to undergo gynecological laparoscopic total hysterectomy under general anesthesia; 5. Self-controlled intravenous analgesic pump is required after surgery; 6. Know the content of the study and voluntarily sign the informed consent form for the study.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of previous difficult airway (e.g., obstructive sleep apnea syndrome), severe respiratory depression (e.g., oxygen saturation <90%), or acute or severe bronchial asthma; 2. Patients with a history of severe cardiovascular and cerebrovascular diseases (such as myocardial infarction or unstable angina, or severe arrhythmia, such as atrioventricular block of the second degree or above, or ischemic stroke of NYHA class II or above); 3. Patients with known or suspected gastrointestinal obstruction, including paralytic ileal obstruction; 4. Patients who are hypersensitive to opioids or any component of the trial drug; 5. Subjects who have had psychiatric disorders (such as schizophrenia, depression, etc.) and cognitive impairment or inability to communicate; 6. Patients with advanced malignant tumors or malignant tumors with extensive metastasis; 7. Subjects with other somatic pain that may affect postoperative pain assessment; 8. Patients with known severe hepatic dysfunction (Childe-Pugh class C); 9. History of drug abuse, alcohol abuse and/or drug abuse within 1 year prior to randomization; 10. Pregnant or lactating female subjects; 11. Subjects who, in the opinion of the investigator, are not eligible to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting;Quality of intra-patient recovery 48h after surgery; | — |
Countries
China
Contacts
Public ContactMei Bin
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed