Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. Stroke patients within 1 month of onset. 3. Clear neurological deficits and symptoms confirmed by CT/MRI. 4. Lesion located in the cerebral hemisphere. 5. Modified Rankin Scale (mRS) score >= 1.
Exclusion criteria
Exclusion criteria: 1. Severe mental disorders. 2. History of severe stroke with significant sequelae (mRS >= 3). 3. Musculoskeletal disorders, other severe neurological diseases, malignancies, or severe cardiac, pulmonary, hepatic, or renal impairments. 4. Brain tumors, traumatic brain injuries, encephalitis, or other organic brain injuries. 5. Alcohol or drug addiction. 6. Inability to complete fNIRS examination. 7. Refusal or inability to be followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Task activation mean;Integral value;Fit coefficients (ß values) based on the General Linear Model (GLM);Brain functional connectivity strength features; | — |
Secondary
| Measure | Time frame |
|---|---|
| The neurological function assessment indicators include motor and sensory function evaluations such as the NIHSS (National Institutes of Health Stroke Scale), mRS (modified Rankin Scale), and Activities of Daily Living (ADL);Cognitive function evaluations such as the MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment);Psychiatric and psychological assessments including depression and anxiety scales, as well as the NPI (Neuropsychiatric Inventory).; | — |
Countries
China
Contacts
Beijing Hospital