Stroke, Brain injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with stroke (ischemic or hemorrhagic) or brain trauma that meet clinical diagnostic criteria; 2. First onset, within 3 months of disease course; 3. Adult patients with tracheotomy (tracheostomy) (aged 18-70 years); 4. Muscle tone score (MAS score) below grade 2; 5. GCS > 8 and able to follow three-step instructions; 6. Stable vital signs; 7. Signed informed consent form (legal representative).
Exclusion criteria
Exclusion criteria: 1. Complications such as severe heart, liver or kidney dysfunction, uncontrolled severe hypertension or diabetes, or other unstable internal diseases may significantly affect the safety, tolerance or cause confusion regarding the reasons for muscle changes; 2. Other clear and independent causes of muscle atrophy exist, including myasthenia gravis, muscular dystrophy, motor neuron disease, recent fractures or orthopedic surgeries affecting the lower limbs; 3. Special treatments that may significantly affect muscle mass have been received within 1 month prior to the start of the study; 4. Other circumstances that make one ineligible to participate in the trial.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index;Cough peak flow value;Manual muscle test; | — |
Primary
| Measure | Time frame |
|---|---|
| Muscle thickness and mass were measured by ultrasound;Lung function; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Kunming Medical University