Allergic rhinitis with asthma
Conditions
Interventions
Experimental group:The experimental group was given fexofenadine hydrochloride dry suspension twice a day, and then oral administration after suspension for 2 weeks.
Control group:The control group was given cetirizine hydrochloride oral solution twice daily for 2 weeks.
Sponsors
The First People's Hospital of Hangzhou
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 6-12 years old, gender is not limited; 2. Meet the diagnostic criteria for allergic rhinitis; 3. Meet the diagnostic criteria for asthma, with the diagnostic criteria referring to the Guidelines for the Prevention and Treatment of Bronchial Asthma (2016 Edition). 4. The asthma control levels are all classified as well - controlled, and the classification criteria refer to the Guidelines for the Prevention and Treatment of Bronchial Asthma (2016 Edition).
Exclusion criteria
Exclusion criteria: 1. Those who do not meet any of the inclusion criteria; 2. Exclude patients with severe liver diseases (ALT or AST or TBIL exceeding 1.5 times the upper limit of normal), kidney diseases (BUN greater than 1.5 times the upper limit of normal), or heart diseases (patients with cardiac function grade 3-4); 3. Have used anti-allergic drugs in the past week; 4. Children who take drugs for other diseases that may affect the results of this study; 5. Children who are allergic to the ingredients contained in this study; 6. The child has participated in other clinical studies; 7. Parent/guardian is unable to complete the record card; 8. Severe patients with obvious metabolic, and immunological, hematologic, cardiovascular, neurological, or respiratory diseases Subjects who, in the opinion of the investigator, may interfere with participation in the study or assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total nasal symptom score;Asthma control level;Therapeutic effectiveness;Subject compliance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Accompanying symptoms;Visual analogue score of symptoms;Time to improvement of rhinitis symptoms;Time to improvement of asthma symptoms;Lung function indicators; | — |
Countries
China
Contacts
Public ContactJiang Chunming
The First People's Hospital of Hangzhou
Outcome results
None listed