Lung cancer
Conditions
Interventions
One-stage group :Bilateral pulmonary lesions resected in one-stage by minimally invasive surgery
Two-stage group :Bilateral pulmonary lesions resected in two-stage by minimally invasive surgery
Sponsors
Department of Thoracic Surgery, China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-75 years; 2.Pathologically or clinically diagnosed with synchronous bilateral non-small cell lung cancer, with at least one surgically indicated lesion in each lung and clinical staging of cT1-2N0-1M0; 3.ASA physical status classification Grade I-II; 4.Charlson Comorbidity Index (CCI) score <= 3; 5.Both bilateral lesions are amenable to minimally invasive surgical resection; 6.Preoperative hematological and cardiopulmonary function assessments within normal ranges, indicating tolerance for bilateral surgical procedures; 7.Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1.Underwent neoadjuvant therapy previously; 2.History of other malignant tumors; 3.Planned bilateral lobectomy; 4.Concomitant severe pulmonary diseases such as pulmonary fibrosis, interstitial pneumonia, or emphysema. Withdrawal criteria: 1. Pathologically confirmed benign, metastatic tumor or small cell lung cancer; 2.Change the surgical plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative complication rate within 30 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical time;Blood loss;Duration of chest tube;Length of stay;Pain score;Anxiety and depression scores ;Quality of life score;5-year overall survival;5-year disease free survival; | — |
Countries
China
Contacts
Public ContactHan Yu
China-Japan Friendship Hospital
Outcome results
None listed