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The Temporal Effects of Artificial Tears on Ocular Biometric Parameters in Patients with Dry Eye and Cataract: A Multicenter Randomized Controlled Trial

The Temporal Effects of Artificial Tears on Ocular Biometric Parameters in Patients with Dry Eye and Cataract: A Multicenter Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106200
Enrollment
Unknown
Registered
2025-07-21
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye with cataract

Interventions

Sodium Hydroxymethyl Cellulose Eye Drop Group:Sodium Hydroxymethyl Cellulose Eye Drop
Sodium Hyaluronate Eye Drop Group:Sodium Hyaluronate Eye Drop
Polyethylene Glycol Eye Drop Group:Polyethylene Glycol Eye Drop

Sponsors

The First Hospital of Putian
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Cataract patients, with normal cognition; 2. Meets TFOS DEWSII. diagnostic criteria for dry eye; 3. Adopt the principle of voluntariness, and have fully understood the use and function of artificial tears and the possible risks.

Exclusion criteria

Exclusion criteria: 1. Anterior segment diseases such as abnormal eyelid position, pterygium, keratitis, etc.; 2. According to LOCSII. classification criteria C4–C5; 3. According to the Emery nuclear hardness grading standard IV.–V., the optical instrument inspection cannot be completed; 4. Posterior subcapsular cataract affecting IOL Master measurements; 5. History of glaucoma, fundus disease, internal eye surgery and ocular trauma; 6. History of contact lens wearing; 7. Presence of punctal blockage or removal 1 month before screening; Continued use of eye drops; immune system disorders, etc.

Design outcomes

Primary

MeasureTime frame
Axial length;Central corneal thickness;Refractive power of the anterior surface of the cornea;

Secondary

MeasureTime frame
Tear film break-up time;Corneal astigmatism;Anterior chamber depth;

Countries

China

Contacts

Public ContactSong Xiaoqing

The First Hospital of Putian

ptsxq@126.com+86 139 0691 1696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026