Polycystic Ovarian Syndrome (PCOS)
Conditions
Interventions
Q1 Group(AMH levels below the 25th percentile):None
Q2 Group(AMH levels between the 25th percentile and the median):None
Q3 Group(AMH levels between the median and the 75th percentile):None
Q4 Group(AMH levels over the 75th percentile):None
Sponsors
The first people's Hospital of Yunnan Province
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Women of childbearing age: 20-35 years old; 2. PCOS patients who meet the Rotterdam criteria; 3. 50kg was detected by Kangrun chemiluminescence method 8.63ng/mL; 5. First cycle IVF/ICSI cycle.
Exclusion criteria
Exclusion criteria: 1.Ovarian or adnexal diseases, such as ovarian masses, untreated severe hydrosalpinx, endometriotic cysts, history of previous ovarian surgery, etc. 2.Uterine or intrauterine abnormalities, including adenomyosis, submucosal myomas, intramural myomas affecting the uterine cavity, genital tract malformations, endometrial polyps, intrauterine adhesions, thin endometrium, etc. 3.Eligibility for preimplantation genetic testing (PGT), such as chromosomal abnormalities in either spouse, recurrent implantation failure (RIF), recurrent spontaneous abortion (RSA), monogenic genetic disorders, etc; 4.Systemic or other organ-related diseases unsuitable for pregnancy if uncontrolled/untreated, including thyroid disorders, diabetes, adrenal abnormalities, chronic diseases, or other conditions contraindicating pregnancy. 5.Recent pretreatment with other medications, such as coenzyme Q10; 6.Severe hepatic or renal insufficiency; 7.Concomitant participation in other clinical trials, or cases deemed ineligible by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Suboptimal Ovarian Response Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| follicular development on D4/5;Follicular output rate;Ovarian sensitivity index;ectopic pregnancy rate;chemical pregnancy rate of fresh embryo transfer cycle;Total Gn dose;follicular development on trigger day;time to the first ovarian response;clinical pregnancy rate of fresh embryo transfer cycle;Number/Rate of good quality blastocyst formation;Number/Rate of good quality embryos on day 3;number of oocyte retrieved;Multiple pregnancy rate;OHSS rate;Number/Rate of available embryos on day 3;Total Gn duration;Gonadotropin (Gn) Dose for First Ovarian Response;Follicular oocyte response index;Number/Rate of blastocyst formation; | — |
Countries
China
Contacts
Public ContactLi Yunxiu
The first people's Hospital of Yunnan Province
Outcome results
None listed