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A Randomized Controlled Trial Investigating the Effects of Transcranial Direct Current Stimulation Combined with Acupuncture on Swallowing Function and Aspiration Status in Post-Brainstem Stroke Patients Based on the Brain-Gut-Lung Axis

A Randomized Controlled Trial Investigating the Effects of Transcranial Direct Current Stimulation Combined with Acupuncture on Swallowing Function and Aspiration Status in Post-Brainstem Stroke Patients Based on the Brain-Gut-Lung Axis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106188
Enrollment
Unknown
Registered
2025-07-18
Start date
2025-07-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Combined Group:1. tDCS (anode placed in the S1M1 area on the healthy side, 2 mA, 20 min/day) 2. Acupuncture (Zusanli, Tianshu, Daheng, Shangjuxu, Quchi, Fenglong, leave needles for 30 minutes/day) 3.
Control Group:Routine swallowing training (30 minutes/session, 1 session/day)

Sponsors

Sichuan Bayi Rehabilitation Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with brainstem stroke who meet the diagnostic criteria of the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke"; 2. Swallowing angiography shows a diagnosis of moderate to severe dysphagia, and eating at least one food has a risk of aspiration; 3. No contraindications to nasal or phonal organic obstruction; 4. Age 40-70 years old; 5. Within 1 year of the course of the disease; 6. Able to comply with the requirements of the executive therapist and adhere to treatment; 7. Patients or their families have signed the informed consent form and meet the requirements of medical ethics.

Exclusion criteria

Exclusion criteria: 1. Those with cardiopulmonary decompensation, infectious diseases, fever, extreme weakness and various bleeding tendencies, and those who have had major epilepsy in the past week; 2. Multiple cerebral infarction lesions, cortex, cerebellum, thalamus and other lesions; 3. Previous history of cerebral hemorrhage, subarachnoid hemorrhage, brain tumor, brain trauma and other neuropsychiatric diseases; 4. Patients with previous nasopharyngeal cancer radiotherapy and head and neck cancer lesions; 5. Previous history of dysphagia; Combined with cognitive dysfunction and aphasia; 6. Severe cardiovascular and lung renal complications; 7. Those who cannot cooperate with examination and treatment.

Design outcomes

Primary

MeasureTime frame
Standard Swallowing Function Evaluation Scale score;GUSS swallowing function assessment scale score;Functional Oral Feeding Scale score;(Penetration-Aspiration Scale,PAS);

Secondary

MeasureTime frame
video-fluoroscopic swallowing study,VFSS;

Countries

China

Contacts

Public ContactGan Li

Sichuan Bayi Rehabilitation Center

2388373274@qq.com+86 158 2813 2037

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026