adenocarcinoma of esophagogastric junction
Conditions
Interventions
early adenocarcinoma of esophagogastric junction group:N/A
healthy control group:N/A
Sponsors
Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age: 20-80 years old, gender not limited; 2. The case group consisted of patients diagnosed as AEGJ by endoscopic examination and pathological diagnosis, and the classification was Siewert II; 3. Patients in the case group met the absolute and expanded indications for ESD treatment; 4.Thirty patients with positive HP and thirty patients with negative HP were included. The judgment criterion was the C13 breath test; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. The initial diagnosis data are incomplete; 2. Patients with a history of upper gastrointestinal surgery or who have received anti-tumor treatment; 3. Those who have received immunosuppressant or antibiotic treatment for more than 4 weeks within the last 6 months; 4. Recent history of oral infections, inflammation, pustules, ulcers, benign/malignant masses, periodontal disease and other oral diseases; 5. Those who have lost more than 8 teeth due to various reasons; 6. Concurrent coronary heart disease, hyperlipidemia, and severe cardiovascular and cerebrovascular diseases; 7. Concurrent complex esophageal diseases or autoimmune diseases; 8. It is difficult to complete the follow-up or there are other factors that affect compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oral microbiota;gastric microbiota; | — |
Countries
China
Contacts
Public ContactXinmin Si
Jiangsu Province Hospital
Outcome results
None listed