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Clinical Study on Quantitative Analysis of Left Atrial Structure and Function in Paroxysmal Atrial Fibrillation Patients Based on P-Wave Index Combined with 2D-STI Technology

Clinical Study on Quantitative Analysis of Left Atrial Structure and Function in Paroxysmal Atrial Fibrillation Patients Based on P-Wave Index Combined with 2D-STI Technology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106166
Enrollment
Unknown
Registered
2025-07-18
Start date
2025-04-08
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paroxysmal atrial fibrillation

Interventions

Sponsors

Jiangsu Province Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for the PAF Group (1) Patients who meet the diagnostic criteria for paroxysmal atrial fibrillation (PAF). (2) Routin eroutine 12-lead electrocardiogram (ECG) shows sinus rhythm. (3) Age between 20 and 80 years, regardless of gender. (4) Informed consent is obtained, and the patient volunteers to participate. The process of obtaining informed consent must comply with Good Clinical Practice (GCP) regulations. 2. Inclusion Criteria for the Control Group Healthy individuals from our hospital's health check-up cohort during the same period, matched by gender and age with the PAF group.

Exclusion criteria

Exclusion criteria: (1) Coronary heart disease. (2)Concomitant valvular heart disease, congenital heart disease, cardiomyopathy, heart failure, etc. (3) Hypertension. (4) Diabetes mellitus. (5) Wolff-Parkinson-White syndrome (pre-excitation syndrome). (6) Recent history of cardiac surgery or radiofrequency ablation for atrial fibrillation. (7)Presence of a cardiac pacemaker. (8)Concomitant organ failure or malignant tumors. (9) Poor compliance, inability to cooperate with follow-up. (10) Current participation in other drug clinical trials.

Design outcomes

Primary

MeasureTime frame
P-wave axis;Left atrial volume index;P-wave peak time;Left atrial strain during conduit phase;P-wave duration;P-wave terminal force in lead;Left atrial strain during reservoir phase;P-wave dispersion;Left atrial strain during contraction phase;

Secondary

MeasureTime frame
Left atrial diameter;Left ventricular ejection fraction;Left ventricular posterior wall thickness;Left ventricular end - diastolic diameter;Interventricular septum thickness;

Countries

China

Contacts

Public ContactDeng Yuanyuan

Jiangsu Province Hospital of Chinese Medicine

271200716@qq.com+86 25 86617141

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026