post-operative neurocognitive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.aged >= 65 years; 2.scheduled for elective total knee arthroplasty; 3.combined with sarcopenia according to Asian Working Group on Sarcopenia (2019); 4.ASA physical status classification I-III; 5.expected length of hospital stay >= 7 days; 6.patients and their families are informed, and have signed the informed consent;
Exclusion criteria
Exclusion criteria: 1.with a history of lower limb fracture surgery; 2.combined with significant organ or system dysfunction; 3.combined with severe cervical or lumbar spine lesions, joint deformities, fractures, severe pain, or primary thrombotic diseases or other situations not suitable for resistance training; 4.gouty arthritis or hemophilia-related arthritis; 5.combined with severe visual or hearing impairments; 6.combined with delirium, dementia, or other severe psychological disorders or personality disorders; 7.combined with severe neurological and muscular system diseases; 8.combined with severe drug dependence, addiction, or alcoholism;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of hospital stay;Activities of Daily Living;knee joint function;incidence of complications;cognitive function;quality of recovery; | — |
Countries
China
Contacts
Affiliated Hospital of Jiangnan University