Head and neck cancer
Conditions
Interventions
Experimental group:medical radiation protectant spray + gargle
Control group:placeb+ gargle
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Diagnosed with head and neck tumors by histopathology; 3. Patients who are receiving radiation therapy for the first time and have irradiation to the oral mucosal area; 4. The patient's Eastern Cooperative Oncology Group (ECOG) score <=3; 5. Able to read, understand, follow study procedures and complete patient diaries independently.
Exclusion criteria
Exclusion criteria: 1. Currently using illegal drugs or currently experiencing alcoholism; 2. Patients with underlying diseases associated with oral infection; 3. The patient is using therapeutic drugs that may cause oral infection; 4. Combined with severe chronic diseases; 5. Patients with mental illness and severe cognitive impairment; 6. The investigator believes that the administration of the study treatment may confound the study results or cause a risk of uncertainty; 7. Patients with a history of head and neck radiotherapy; 8. Patients who refuse to be followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oral mucositis; | — |
Secondary
| Measure | Time frame |
|---|---|
| nutritional status assessment;the immune function; | — |
Countries
China
Contacts
Public ContactXin Jiang
The First Hospital of Jilin University
Outcome results
None listed