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Cross-Sectional Study on Exploring Individualized Dosing Methods for Methotrexate in Rheumatoid Arthritis Treatment Based on Blood Drug Concentration Monitoring

Cross-Sectional Study on Exploring Individualized Dosing Methods for Methotrexate in Rheumatoid Arthritis Treatment Based on Blood Drug Concentration Monitoring

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106145
Enrollment
Unknown
Registered
2025-07-18
Start date
2025-07-18
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Interventions

Sponsors

The Second Affiliated Hospital of the Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients admitted to the Department of Dermatology, Rheumatology and Immunology, gender is not limited, age >=18 years 2. Patients who meet the diagnostic criteria for rheumatoid arthritis from the American College of Rheumatology (ACR) or the European League Against Rheumatism (EULAR). 3. Methotrexate has been taken for more than 3 months 4. Patients voluntarily participate in this study and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1. Concomitant use of biologically modifying antirheumatic drugs (DMARDs) or targeted synthetic disease-modifying antirheumatic drugs 2. Concomitant use of glucocorticoid prednisone (or equivalent other hormones) greater than 10mg 3. The patient's case data is incomplete

Design outcomes

Primary

MeasureTime frame
Disease activity score (DAS);Methotrexate plasma concentration;

Countries

China

Contacts

Public ContactFei Ye

The Second Affiliated Hospital of the Army Medical University

yefei198602@126.com+86 187 2576 7250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026