Acute Herpes Zoster Neuralgia, AHZN
Conditions
Interventions
Observation group (Dex group):Subjects in the DEX group received dexmedetomidine nasal spray in a sitting position at 9 p.m. and 30 minutes before operation, respectively
Control group (NS group):Subjects in the NS group received normal saline nasal spray administration in a sitting position at 9 p.m. and 30 minutes before operation
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 50-59 years old; 2. Confirmed diagnosis of AHN (course of illness =7 points; 5. DRG-PRF treatment is planned.
Exclusion criteria
Exclusion criteria: 1. Patients with bradycardia; 2. History of a2 receptor antagonist use; 3. Nasal anatomical abnormalities; 4. Mental illness; 5. Patients with severe coagulation dysfunction and cardiopulmonary insufficiency; 6. Patients with malignant tumors and cachexia; 7. Infection at the puncture site; 8. Pregnant and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ramsay score of subjects at the start of DRG-PRF surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Polysomnography;numerical rating scale, NRS;Interleukin-6;neuron-specific enolase,NSE;Interleukin-10;Pittsburgh sleep quality index,PSQI;Interleukin-1ß;a tumor necrosis factor,TNF-a; | — |
Countries
China
Contacts
Public ContactYanwei Yin
The Affiliated Hospital of Qingdao University
Outcome results
None listed